Anderson noted he “wanted to take this franchise global” and how they shot across the world, including sequences in Times Square and Red Square. He also revealed Retribution picks up directly after the events of the last film, with “an epic battle on the Arcadia” before going to “a very unusual and unexpected place.”
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He also noted that, as the trailer hints, we will see the world before the infection, allowing the, “Return of a lot of classic characters from both the Resident Evil videos games and films.” It’s not clear if Michelle Rodriguez only appears in these flashbacks, as Anderson said, “She’s a big part of this movie.”
Anderson and Jovovich mentioned what a huge Call of Duty player Rodriguez is and the challenge of getting her to put down the controller and “put a real machine gun in her hand,” as Anderson put it. Jovovich laughed that they’d be asking for Rodriguez to come to set and she’d exclaim, “No man, I’m about to beat this Belgian dude!”
While Anderson and Jovovich said there was no guarantee of a sixth film until they see how this one does, Anderson did say, “This is very much the beginning of the end,” and that Retribution was intended as the penultimate chapter. “This movie sets up what we hope is a specular finale.”
Anderson laughed that in the discussed Resident Evil 6, “Lots of people die.” To which Jovivich replied, “Except me, right?”
Source:ign